Caulophyllum thalictroides – Blue Cohosh

Written by admin

November 12, 2025

PARTS USED:

  • Root

USES:

Anti-inflammatory

Antispasmodic

  • Abdominal cramping, gas
  • Leg cramps
  • Colic
  • Asthma, bronchitis, cough

Neuro

  • Activation of microglial cells – may prove

useful for neurodegenerative diseases

  • Alzheimer’s
  • Parkinson’s
  • Lewy-body Dementia
  • Has proven helpful in post-op pain

Musculoskeletal

  • Muscle spasms
  • Rheumatic conditions

Integumentary

  • Promotes wound healing by improving circulation

Reproductive

  • Amenorrhea/dysmenorrhea
  • Facilitates childbirth – brings on contractions
  • Helps minimize excessive menstrual and post-natal bleeding
  • Pelvic inflammatory disease
  • Endometriosis
  • Ovarian and uterine tonic
    • Useful in any condition where there is loss of tone, including mild prolapse
    • Helps promote normal levels of estrogen and progesterone
    • Regulates the luteal phase of the cycle
  • Promotes efficient evacuation of the endometrium during menstruation
  • Congestive dysmenorrhea (used as an astringent)
  • Emmenagogue – brings on delayed menses

Oncology

  • Shows promise in the treatment of estrogen-independent breast cancer
    • Apoptosis
    • Inhibits cell proliferation

PREPARATION:

    • Decoction
    • Tincture

    Notes: 

    *   Only use as a small portion of any formula – no more than 20%

    *   Caulophine (active ingredient) is easily absorbed after oral administration – effects work relatively quickly; however, it is eliminated from the body slowly, so there is a potential for buildup. Space doses apart

    *    Does no extract well in oils

            SIDE EFFECTS AND TOXICITY:

              • Do not use in early pregnancy – can be an abortifacient; OK in the last 2-4 weeks
              • Neonatal CHF has been linked to an overdose of this herb during labour
              • May elevate BP and glucose levels
              • Known to inhibit cyp450, the enzyme that helps metabolize drugs and toxins – may lead to toxic doses of drugs in the body
              • Cardiac glycosides can induce fetal complications if taken in excessive doses

              MISCELLANEOUS:

              • Many Indian tribes used this herb as an agent for the relief of colic and cramps in children
              • Also known as squaw root or papoose root
              • Considered an ‘at risk’ plant in the wild
              • Blue cohosh is listed in the British Herbal Pharmacopoeia (1983) as a spasmolytic and emmenagogue

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